What is the function of reverse transcriptase?

Study for the Praxis II Biology (5235) Test. Use flashcards and multiple-choice questions with helpful hints and explanations. Get exam-ready!

Reverse transcriptase is an enzyme that plays a crucial role in the life cycle of retroviruses and certain cellular processes. Its primary function is to transcribe DNA from an RNA template, a process that is the reverse of the typical transcription where DNA is used to produce RNA. This enables the synthesis of complementary DNA (cDNA) from RNA molecules.

In the context of retroviruses, after the virus enters a host cell, reverse transcriptase synthesizes DNA from the viral RNA genome. This DNA can then integrate into the host's genome, allowing for the viral genetic material to be replicated along with the host's DNA during cellular division. This is a significant aspect of how retroviruses, such as HIV, propagate and sustain infections within a host organism.

The other answer choices suggest functions that are not associated with reverse transcriptase, such as replicating DNA from DNA (which is usually performed by DNA polymerases), transcribing RNA from DNA (typically carried out by RNA polymerase), or editing messenger RNA (which involves other enzymes like spliceosomes or specific RNA-binding proteins). Understanding the unique role of reverse transcriptase helps clarify its importance in both molecular biology and virology.

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