In which part of the cell does glycolysis occur?

Study for the Praxis II Biology (5235) Test. Use flashcards and multiple-choice questions with helpful hints and explanations. Get exam-ready!

Glycolysis occurs in the cytoplasm of the cell. This metabolic pathway involves the breakdown of glucose into pyruvate, and it is the first step in cellular respiration. The reaction does not require oxygen, making it an anaerobic process, and because it takes place in the cytoplasm, it can occur in both prokaryotic and eukaryotic cells.

The other cell parts mentioned are involved in different cellular processes. For example, the mitochondria are where aerobic respiration occurs, specifically the Krebs cycle and oxidative phosphorylation, which follow glycolysis when oxygen is available. The nucleus is mainly responsible for housing the cell's genetic material and facilitating processes such as transcription. The endoplasmic reticulum, which comes in two forms (rough and smooth), is involved in the synthesis of proteins and lipids but is not related to the glycolytic process. Therefore, the cytoplasm is the correct environment for glycolysis to occur.

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